As proven below, by choosing InertCore C18, you can be assured that you are using one of the most trusted and enduring UHPLC, LC/MS columns in the industry.
“The new Aeris columns are ‘plug and play,’ requiring very little work in method transfer,” comments Kari Kelly, brand manager for Phenomenex. Many core shell columns in the market often show irreproducible chromatographic results on retention time or peak shapes from batch-to-batch. This efficiency gain allows chromatographers to maximize the performance out of their HPLC/UHPLC system by using the right particle morphology for the. On UHPLC systems, the 1.7-micron Aeris particles can deliver higher peak capacities than fully porous sub-2 micron columns.
Aeris PEPTIDE 3.6-micron particles offer high performance at backpressures compatible with both HPLC and UHPLC instruments. Kirkland proposed better efficiency of 30 40mm core-shell particles compared. The novel XB-C18 stationary phase provides the ideal surface chemistry for resolving peptides. Because the 3.6-micron core-shell particles produce lower backpressures than traditional media, longer or coupled columns can be used to increase resolving power on both HPLC and UHPLC instruments.Īeris PEPTIDE 3.6-micron and 1.7-micron columns, designed with a small pore size, are recommended for the separation of low molecular weight peptides and for peptide mapping. Aeris WIDEPORE 3.6-micron core-shell columns are optimized for the separation of intact proteins and polypeptides, and are available in three selectivity’s – XB-C18, XB-C8 and C4. With virtually no bleed, Aeris columns are highly compatible with MS.Īeris columns are offered in wide- and small-pore configurations. Used in conjunction with high mobile phase flow rates, core-shell particles can reduce the amount of analysis time without impacting upon rates of separation efficiency or generating extreme back-pressures. While this may sound tricky, core-shell technologies provide a low-pressure, high efficiency solution to this particular problem. These new high-performance columns deliver high resolution and peak capacities, producing sub-2 micron results on any LC instrument. Today, the vast majority of chromatographers seek to lower costs and increase productivity simultaneously. has introduced Aeris™ – core-shell HPLC/UHPLC columns specially designed for the analysis of proteins and peptides. UHPLC analyses on porous silica gel with particle size In this work we look at the ability to achieve fast, selective, sensitive LC methods with these core-shell products for a range of pharmaceutical drugs. Shim-pack HPLC Column Guidebook - High Performance Liquid Chromatography Columns PDF. HPLC analyses on porous silica gel with particle size >2.9μm The introduction of core-shell particles into the separation sciences has lead to potential improvements in all of the requirements above. Maximize LC Separation Performance with Core Shell Technology.Our noteworthy HPLC columns are dedicated for a wide range of applications and can be presented as follows: 4 Recipes for Food Technology Middle Secondary Workbook Chemistry 1 Units.
High-performance liquid chromatography, or HPLC, is a chromatographic technique to separate a mixture of compounds and is used in biochemistry and analytical chemistry to identify, quantify and purify the individual components of the mixture. protons in the nucleus of a given atom 25 VCE Chemistry enables students. Our unique phases are developed to provide different selectivities for successful separations of the most complex mixtures and challenging analytes under normal or reversed phase conditions. Want to benefit from the best HPLC or UHPLC innovations and get the highest quality products available? In contrast to the typical silica-based LC particles, core-shell particles consist of a solid, impermeable inner silica core that is surrounded by an outer shell of conventional fully porous silica (Figure 1). ANALYTICAL SCIENCES > Liquid Chromatography > Analytical HPLC Columns conventional HPLC systems What is this core-shell technology of which you speak I’m glad you asked that.
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